Creeping substitution

This definition details the process of bone or bone graft substitute biomaterials remodeling by osteoclastic resorption and creation of new vascular channels with osteoblastic bone formation resulting in new haversian systems and it is the method by which strong cortical bone is formed from grafted material or bone graft substitute biomaterials.

• The osteoclastic resorption of dead bone from the allograft and its replacement by new living bone made by osteoblasts from the host.
• Gradual penetration across a fracture site by osteogenic tissue followed by bone formation